External Fixator Clamp Reuse Degrades Clamp Mechanical Performance

Cleaning patch-clamp pipettes for immediate reuse

Patch-clamp recording has enabled single-cell electrical, morphological and genetic studies at unparalleled resolution. Yet it remains a laborious and low-throughput technique, making it largely impractical for large-scale measurements such as cell type and connectivity characterization of neurons in the brain. Specifically, the technique is critically limited by the ubiquitous practice of manu...

Open proximal & distal fractures of tibia treated with Naseer Awais External Fixator with T-clamp.

OBJECTIVE To compare the outcome of the open proximal and distal fractures of tibia treated by Nasser Awais External Fixtator with T-clamp. METHODS The descriptive case series was conducted from August 2009 to July 2012 at Department of Orthopaedic Surgery & Traumatology, Liaquat University of Medical & Health Sciences, Jamshoro, and comprised in-patients of open proximal and distal fractures...

How a DNA polymerase clamp loader opens a sliding clamp.

Processive chromosomal replication relies on sliding DNA clamps, which are loaded onto DNA by pentameric clamp loader complexes belonging to the AAA+ family of adenosine triphosphatases (ATPases). We present structures for the ATP-bound state of the clamp loader complex from bacteriophage T4, bound to an open clamp and primer-template DNA. The clamp loader traps a spiral conformation of the ope...

Tarsorrhaphy lid clamp.

Tarsorrhaphy is finding increasing indications because of the resultant improvement in comeal metabolic activity and also the protective cover given to the cornea. Different techniques' have been described for performing the tarsorrhaphy, but the basic principle remains the same. It is to produce adhesions between the 2 lid margins by creating a raw intermarginal strip on the 2 lids. Tarsorrhap...

A New Eyelid Clamp